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1

Expression analysis of inflammasomes in experimental models of inflammatory and fibrotic liver disease

Boaru, Sorina Georgiana, Borkham-Kamphorst, Erawan, Tihaa, Lidia, Haas, Ute, Weiskirchen, Ralf

Journal:

Journal of Inflammation

Year:

2012

Language:

english

File:

PDF, 2.31 MB

english, 2012

2

Expression and functional analysis of endoglin in isolated liver cells and its involvement in fibrogenic Smad signalling

Steffen K. Meurer, Lidia Tihaa, Erawan Borkham-Kamphorst, Ralf Weiskirchen

Journal:

Cellular Signalling

Year:

2011

Language:

english

File:

PDF, 2.98 MB

english, 2011

3

The anti-fibrotic effects of CCN1/CYR61 in primary portal myofibroblasts are mediated through induction of reactive oxygen species resulting in cellular senescence, apoptosis and attenuated TGF-β signaling

Borkham-Kamphorst, Erawan, Schaffrath, Christian, Van de Leur, Eddy, Haas, Ute, Tihaa, Lidia, Meurer, Steffen K., Nevzorova, Yulia A., Liedtke, Christian, Weiskirchen, Ralf

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular Cell Research

Year:

2014

Language:

english

File:

PDF, 3.08 MB

english, 2014

4

NLRP3 inflammasome expression is driven by NF-κB in cultured hepatocytes

Boaru, Sorina Georgiana, Borkham-Kamphorst, Erawan, Van de Leur, Eddy, Lehnen, Eric, Liedtke, Christian, Weiskirchen, Ralf

Journal:

Biochemical and Biophysical Research Communications

Year:

2015

Language:

english

File:

PDF, 2.42 MB

english, 2015

5

A Novel, Dual Role of CCN3 in Experimental Glomerulonephritis: Pro-Angiogenic and Antimesangioproliferative Effects

Claudia R.C. van Roeyen, Peter Boor, Erawan Borkham-Kamphorst, Song Rong, Uta Kunter, Ina V. Martin, Ana Kaitovic, Stefan Fleckenstein, Bernard Perbal, Christian Trautwein, Ralf Weiskirchen, Tammo Ost

Journal:

The American Journal of Pathology

Year:

2012

Language:

english

File:

PDF, 4.24 MB

english, 2012

6

Cryopreservation of hepatic stellate cells

Svenja Neyzen, Eddy Van de Leur, Erawan Borkham-Kamphorst, Jens Herrmann, Günter Hollweg, Axel M. Gressner, Ralf Weiskirchen

Journal:

Journal of Hepatology

Year:

2006

Language:

english

File:

PDF, 425 KB

english, 2006

7

Adenoviral CCN3/NOV gene transfer fails to mitigate liver fibrosis in an experimental bile duct ligation model because of hepatocyte apoptosis

Erawan Borkham-Kamphorst, Sebastian Huss, Eddy Van de Leur, Ute Haas, Ralf Weiskirchen

Journal:

Liver International

Year:

2012

Language:

english

File:

PDF, 1.18 MB

english, 2012

8

N-Glycosylation of Lipocalin 2 Is Not Required for Secretion or Exosome Targeting

Borkham-Kamphorst, Erawan, Van de Leur, Eddy, Meurer, Steffen K., Buhl, Eva M., Weiskirchen, Ralf

Journal:

Frontiers in Pharmacology

Year:

2018

Language:

english

File:

PDF, 4.24 MB

english, 2018

9

Human mesenchymal stem cells towards non-alcoholic steatohepatitis in an immunodeficient mouse model

Winkler, Sandra, Borkham-Kamphorst, Erawan, Stock, Peggy, Brückner, Sandra, Dollinger, Matthias, Weiskirchen, Ralf, Christ, Bruno

Journal:

Experimental Cell Research

Year:

2014

Language:

english

File:

PDF, 7.60 MB

english, 2014

10

Factor VII activating protease (FSAP) exerts anti-inflammatory and anti-fibrotic effects in liver fibrosis in mice and men

Borkham-Kamphorst, Erawan, Zimmermann, Henning W., Gassler, Nikolaus, Bissels, Ute, Bosio, Andreas, Tacke, Frank, Weiskirchen, Ralf, Kanse, Sandip M.

Journal:

Journal of Hepatology

Year:

2013

Language:

english

File:

PDF, 1.13 MB

english, 2013

11

Lipocalin-2 (LCN2) regulates PLIN5 expression and intracellular lipid droplet formation in the liver

Asimakopoulou, Anastasia, Borkham-Kamphorst, Erawan, Henning, Marc, Yagmur, Eray, Gassler, Nikolaus, Liedtke, Christian, Berger, Thorsten, Mak, Tak W., Weiskirchen, Ralf

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids

Year:

2014

Language:

english

File:

PDF, 3.84 MB

english, 2014

12

Identification of Ppar Î³ -modulated miRNA hubs that target the fibrotic tumor microenvironment

Winkler, Ivana, Bitter, Catrin, Winkler, Sebastian, Weichenhan, Dieter, Thavamani, Abhishek, Hengstler, Jan G., Borkham-Kamphorst, Erawan, Kohlbacher, Oliver, Plass, Christoph, Geffers, Robert, Weiski

Journal:

Proceedings of the National Academy of Sciences

Year:

2020

File:

PDF, 1.78 MB

2020

13

Proapoptotic effects of the chemokine, CXCL 10 are mediated by the noncognate receptor TLR4 in hepatocytes

Sahin, Hacer, Borkham-Kamphorst, Erawan, do O, Nicole T., Berres, Marie-Luise, Kaldenbach, Michaela, Schmitz, Petra, Weiskirchen, Ralf, Liedtke, Christian, Streetz, Konrad L., Maedler, Kathrin, Trautw

Journal:

Year:

2013

Language:

english

File:

PDF, 918 KB

english, 2013

14

CCN1/CYR61 overexpression in hepatic stellate cells induces ER stress-related apoptosis

Borkham-Kamphorst, Erawan, Steffen, Bettina T., Van de Leur, Eddy, Haas, Ute, Tihaa, Lidia, Friedman, Scott L., Weiskirchen, Ralf

Journal:

Cellular Signalling

Year:

2016

Language:

english

File:

PDF, 1.89 MB

english, 2016

15

Altered mitochondrial and peroxisomal integrity in lipocalin-2-deficient mice with hepatic steatosis

Asimakopoulou, Anastasia, Fülöp, Annabelle, Borkham-Kamphorst, Erawan, de Leur, Eddy Van, Gassler, Nikolaus, Berger, Thorsten, Beine, Birte, Meyer, Helmut E., Mak, Tak W., Hopf, Carsten, Henkel, Corin

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease

Year:

2017

Language:

english

File:

PDF, 1.91 MB

english, 2017

16

Platelet-derived growth factor isoform expression in carbon tetrachloride-induced chronic liver injury

Borkham-Kamphorst, Erawan, Kovalenko, Evgenia, van Roeyen, Claudia R C, Gassler, Nikolaus, Bomble, Michael, Ostendorf, Tammo, Floege, Jürgen, Gressner, Axel M, Weiskirchen, Ralf

Journal:

Laboratory Investigation

Year:

2008

Language:

english

File:

PDF, 582 KB

english, 2008

17

Platelet-derived growth factor-D modulates extracellular matrix homeostasis and remodeling through TIMP-1 induction and attenuation of MMP-2 and MMP-9 gelatinase activities

Borkham-Kamphorst, Erawan, Alexi, Pascal, Tihaa, Lidia, Haas, Ute, Weiskirchen, Ralf

Journal:

Biochemical and Biophysical Research Communications

Year:

2015

Language:

english

File:

PDF, 1.62 MB

english, 2015

18

Adenoviral CCN gene transfers induce in vitro and in vivo endoplasmic reticulum stress and unfolded protein response

Borkham-Kamphorst, Erawan, Steffen, Bettina Therese, Van de Leur, Eddy, Tihaa, Lidia, Haas, Ute, Woitok, Marius M., Meurer, Steffen K., Weiskirchen, Ralf

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular Cell Research

Year:

2016

Language:

english

File:

PDF, 1.86 MB

english, 2016

19

Pharmacological Intervention in Hepatic Stellate Cell Activation and Hepatic Fibrosis

Schon, Hans-Theo, Bartneck, Matthias, Borkham-Kamphorst, Erawan, Nattermann, Jacob, Lammers, Twan, Tacke, Frank, Weiskirchen, Ralf

Journal:

Frontiers in Pharmacology

Year:

2016

Language:

english

File:

PDF, 4.72 MB

english, 2016

20

Dominant-negative soluble PDGF-β receptor inhibits hepatic stellate cell activation and attenuates liver fibrosis

Borkham-Kamphorst, Erawan, Herrmann, Jens, Stoll, Doris, Treptau, Jens, Gressner, Axel M, Weiskirchen, Ralf

Journal:

Laboratory Investigation

Year:

2004

Language:

english

File:

PDF, 583 KB

english, 2004

21

Corrigendum to “Factor VII activating protease (FSAP) exerts anti-inflammatory and anti-fibrotic effects in liver fibrosis in mice and men” [J Hepatol 2013;58:104–111]

Borkham-Kamphorst, Erawan, Zimmermann, Henning W., Gassler, Nikolaus, Bissels, Ute, Bosio, Andreas, Tacke, Frank, Weiskirchen, Ralf, Kanse, Sandip M.

Journal:

Journal of Hepatology

Year:

2014

Language:

english

File:

PDF, 206 KB

english, 2014

22

Bile Duct Ligation in Mice: Induction of Inflammatory Liver Injury and Fibrosis by Obstructive Cholestasis

Tag, Carmen G., Sauer-Lehnen, Sibille, Weiskirchen, Sabine, Borkham-Kamphorst, Erawan, Tolba, René H., Tacke, Frank, Weiskirchen, Ralf

Journal:

Journal of Visualized Experiments

Year:

2015

Language:

english

File:

PDF, 1.01 MB

english, 2015

23

Inhibitory effect of soluble PDGF-β receptor in culture-activated hepatic stellate cells

Erawan Borkham-Kamphorst, Doris Stoll, Axel M. Gressner, Ralf Weiskirchen

Journal:

Biochemical and Biophysical Research Communications

Year:

2004

Language:

english

File:

PDF, 2.36 MB

english, 2004

24

The expression of CSRP2 encoding the LIM domain protein CRP2 is mediated by TGF-β in smooth muscle and hepatic stellate cells

Jens Herrmann, Erawan Borkham-Kamphorst, Ute Haas, Eddy Van de Leur, Mario F. Fraga, Manel Esteller, Axel M. Gressner, Ralf Weiskirchen

Journal:

Biochemical and Biophysical Research Communications

Year:

2006

Language:

english

File:

PDF, 636 KB

english, 2006

25

Disruption of intermolecular disulfide bonds in PDGF-BB dimers by N-acetyl-l-cysteine does not prevent PDGF signaling in cultured hepatic stellate cells

Erawan Borkham-Kamphorst, Steffen K. Meurer, Axel M. Gressner, Ralf Weiskirchen

Journal:

Biochemical and Biophysical Research Communications

Year:

2005

Language:

english

File:

PDF, 336 KB

english, 2005

26

CCN3/NOV small interfering RNA enhances fibrogenic gene expression in primary hepatic stellate cells and cirrhotic fat storing cell line CFSC

Erawan Borkham-Kamphorst, Claudia R. van Roeyen, Eddy Van de Leur, Jürgen Floege, Ralf Weiskirchen

Journal:

Journal of Cell Communication and Signaling

Year:

2012

Language:

english

File:

PDF, 734 KB

english, 2012

27

Induction of lipocalin-2 expression in acute and chronic experimental liver injury moderated by pro-inflammatory cytokines interleukin-1β through nuclear factor-κB activation

Erawan Borkham-Kamphorst, Falko Drews, Ralf Weiskirchen

Journal:

Liver International

Year:

2011

Language:

english

File:

PDF, 760 KB

english, 2011

28

Proteomic profiling in Lipocalin 2 deficient mice under normal and inflammatory conditions

Labbus, Kirsten, Henning, Marc, Borkham-Kamphorst, Erawan, Geisler, Cordelia, Berger, Thorsten, Mak, Tak W., Knüchel, Ruth, Meyer, Helmut E., Weiskirchen, Ralf, Henkel, Corinna

Journal:

Journal of Proteomics

Year:

2013

Language:

english

File:

PDF, 926 KB

english, 2013

29

PDGF-D signaling in portal myofibroblasts and hepatic stellate cells proves identical to PDGF-B via both PDGF receptor type α and β

Borkham-Kamphorst, Erawan, Meurer, Steffen K., Van de Leur, Eddy, Haas, Ute, Tihaa, Lidia, Weiskirchen, Ralf

Journal:

Cellular Signalling

Year:

2015

Language:

english

File:

PDF, 1.64 MB

english, 2015

30

Chronic Carbon Tetrachloride Applications Induced Hepatocyte Apoptosis in Lipocalin 2 Null Mice Through Endoplasmic Reticulum Stress and Unfolded Protein Response

Borkham-Kamphorst, Erawan, Haas, Ute, Van de Leur, Eddy, Trevanich, Anothai, Weiskirchen, Ralf

Journal:

International Journal of Molecular Sciences

Year:

2020

File:

PDF, 6.92 MB

2020

31

Chemokine Cxcl9 attenuates liver fibrosis-associated angiogenesis in mice

Hacer Sahin, Erawan Borkham-Kamphorst, Christoph Kuppe, Mirko Moreno Zaldivar, Christoph Grouls, Muhammad Al-samman, Andreas Nellen, Petra Schmitz, Daniel Heinrichs, Marie-Luise Berres, Dennis Dolesch

Journal:

Year:

2012

Language:

english

File:

PDF, 1.49 MB

english, 2012

32

Platelet-Derived Growth Factor (PDGF)-C Neutralization Reveals Differential Roles of PDGF Receptors in Liver and Kidney Fibrosis

Martin, Ina V., Borkham-Kamphorst, Erawan, Zok, Stephanie, van Roeyen, Claudia R.C., Eriksson, Ulf, Boor, Peter, Hittatiya, Kanishka, Fischer, Hans-Peter, Wasmuth, Hermann E., Weiskirchen, Ralf, Eitne

Journal:

The American Journal of Pathology

Year:

2013

Language:

english

File:

PDF, 1.35 MB

english, 2013

33

Protective effects of lipocalin-2 (LCN2) in acute liver injury suggest a novel function in liver homeostasis

Borkham-Kamphorst, Erawan, van de Leur, Eddy, Zimmermann, Henning W., Karlmark, Karlin Raja, Tihaa, Lidia, Haas, Ute, Tacke, Frank, Berger, Thorsten, Mak, Tak W., Weiskirchen, Ralf

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease

Year:

2013

Language:

english

File:

PDF, 2.36 MB

english, 2013

34

Lipocalin-2 (NGAL/LCN2), a “help-me” signal in organ inflammation

Asimakopoulou, Anastasia, Borkham-Kamphorst, Erawan, Tacke, Frank, Weiskirchen, Ralf

Journal:

Year:

2016

Language:

english

File:

PDF, 746 KB

english, 2016

35

Corrigendum to “Inhibitory effect of soluble PDGF-β receptor in culture-activated hepatic stellate cells” [Biochem. Biophys. Res. Commun. 317 (2004) 451–462]

Erawan Borkham-Kamphorst, Doris Stoll, Axel M. Gressner, Ralf Weiskirchen

Journal:

Biochemical and Biophysical Research Communications

Year:

2004

Language:

english

File:

PDF, 209 KB

english, 2004

36

The PDGF system and its antagonists in liver fibrosis

Borkham-Kamphorst, Erawan, Weiskirchen, Ralf

Journal:

Cytokine & Growth Factor Reviews

Year:

2015

Language:

english

File:

PDF, 1.85 MB

english, 2015

37

Portal myofibroblasts are sensitive to CCN-mediated endoplasmic reticulum stress-related apoptosis with potential to attenuate biliary fibrogenesis

Borkham-Kamphorst, Erawan, Steffen, Bettina Therese, van de Leur, Eddy, Haas, Ute, Weiskirchen, Ralf

Journal:

Cellular Signalling

Year:

2018

Language:

english

File:

PDF, 25.08 MB

english, 2018

38

Liver parenchymal cells lacking Lipocalin 2 (LCN2) are prone to endoplasmic reticulum stress and unfolded protein response

Borkham-Kamphorst, Erawan, Van de Leur, Eddy, Haas, Ute, Weiskirchen, Ralf

Journal:

Cellular Signalling

Year:

2019

Language:

english

File:

PDF, 16.32 MB

english, 2019

39

Dysregulated mesenchymal PDGFR‐β drives kidney fibrosis

Buhl, Eva M, Djudjaj, Sonja, Klinkhammer, Barbara M, Ermert, Katja, Puelles, Victor G, Lindenmeyer, Maja T, Cohen, Clemens D, He, Chaoyong, Borkham‐Kamphorst, Erawan, Weiskirchen, Ralf, Denecke, Bernd

Journal:

EMBO Molecular Medicine

Year:

2020

Language:

english

File:

PDF, 3.73 MB

english, 2020

40

Pro-fibrogenic potential of PDGF-D in liver fibrosis

Erawan Borkham-Kamphorst, Claudia R.C. van Roeyen, Tammo Ostendorf, Jürgen Floege, Axel M. Gressner, Ralf Weiskirchen

Journal:

Journal of Hepatology

Year:

2007

Language:

english

File:

PDF, 1.53 MB

english, 2007

41

Data on Lipocalin 2 and phosphatidylinositol 3-kinase signaling in a methionine- and choline-deficient model of non-alcoholic steatohepatitis

Asimakopoulou, Anastasia, Borkham-Kamphorst, Erawan, de Leur, Eddy Van, Weiskirchen, Ralf

Journal:

Year:

2017

Language:

english

File:

PDF, 619 KB

english, 2017

42

Î±2-Adrenergic Receptor in Liver Fibrosis: Implications for the Adrenoblocker Mesedin

Schwinghammer, Ute A., Melkonyan, Magda M., Hunanyan, Lilit, Tremmel, Roman, Weiskirchen, Ralf, Borkham-Kamphorst, Erawan, Schaeffeler, Elke, Seferyan, Torgom, Mikulits, Wolfgang, Yenkoyan, Konstantin

Journal:

Year:

2020

Language:

english

File:

PDF, 6.32 MB

english, 2020

43

Antisense strategy against PDGF B-chain proves effective in preventing experimental liver fibrogenesis

Erawan Borkham-Kamphorst, Doris Stoll, Axel M. Gressner, Ralf Weiskirchen

Journal:

Biochemical and Biophysical Research Communications

Year:

2004

Language:

english

File:

PDF, 763 KB

english, 2004

44

The role of PDGF-D in healthy and fibrotic kidneys

Buhl, Eva M., Djudjaj, Sonja, Babickova, Janka, Klinkhammer, Barbara M., Folestad, Erika, Borkham-Kamphorst, Erawan, Weiskirchen, Ralf, Hudkins, Kelly, Alpers, Charles E., Eriksson, Ulf, Floege, Jürge

Journal:

Kidney International

Year:

2016

Language:

english

File:

PDF, 6.57 MB

english, 2016

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